1 2169 123 THE EFFECTS OF YOGA IN PREVENTION OF PREGNANCY COMPLICATIONS IN HIGH-RISK PREGNANCIES: A RANDOMIZED CONTROLLED TRIAL. OBJECTIVE: WHILE PREVIOUS STUDIES HAVE SHOWN THE POTENTIAL EFFECTS OF YOGA IN NORMAL PREGNANCIES, THIS RANDOMIZED CONTROLLED TRIAL INVESTIGATED THE EFFECTS OF YOGA IN PREVENTION OF PREGNANCY COMPLICATIONS IN HIGH-RISK PREGNANCIES FOR THE FIRST TIME. METHODS: 68 HIGH-RISK PREGNANT WOMEN WERE RECRUITED FROM TWO MATERNITY HOSPITALS IN BENGALURU, INDIA AND WERE RANDOMIZED INTO YOGA AND CONTROL GROUPS. THE YOGA GROUP (N=30) RECEIVED STANDARD CARE PLUS ONE-HOUR YOGA SESSIONS, THREE TIMES A WEEK, FROM THE 12TH TO THE 28TH WEEK OF GESTATION. THE CONTROL GROUP (N=38) RECEIVED STANDARD CARE PLUS CONVENTIONAL ANTENATAL EXERCISES (WALKING) DURING THE SAME PERIOD. RESULTS: SIGNIFICANTLY FEWER PREGNANCY INDUCED HYPERTENSION (PIH), PREECLAMPSIA, GESTATIONAL DIABETES (GDM) AND INTRAUTERINE GROWTH RESTRICTION (IUGR) CASES WERE OBSERVED IN THE YOGA GROUP (P=0.018, 0.042, 0.049, 0.05 RESPECTIVELY). SIGNIFICANTLY FEWER SMALL FOR GESTATIONAL AGE (SGA) BABIES AND NEWBORNS WITH LOW APGAR SCORES (P=0.006) WERE BORN IN THE YOGA GROUP (P=0.033). CONCLUSION: THIS FIRST RANDOMIZED STUDY OF YOGA IN HIGH-RISK PREGNANCY HAS SHOWN THAT YOGA CAN POTENTIALLY BE AN EFFECTIVE THERAPY IN REDUCING HYPERTENSIVE RELATED COMPLICATIONS OF PREGNANCY AND IMPROVING FETAL OUTCOMES. ADDITIONAL DATA IS NEEDED TO CONFIRM THESE RESULTS AND BETTER EXPLAIN THE MECHANISM OF ACTION OF YOGA IN THIS IMPORTANT AREA.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
2  613  28 DEVELOPMENT OF A YOGA PROGRAM FOR TYPE-2 DIABETES PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA. INTRODUCTION: MANY INDIANS ARE AT HIGH-RISK OF TYPE-2 DIABETES MELLITUS (T2DM). YOGA IS AN ANCIENT INDIAN MIND-BODY DISCIPLINE, THAT HAS BEEN ASSOCIATED WITH IMPROVED GLUCOSE LEVELS AND CAN HELP TO PREVENT T2DM. THE STUDY AIMED TO SYSTEMATICALLY DEVELOP A YOGA PROGRAM FOR T2DM PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA USING A COMPLEX INTERVENTION DEVELOPMENT APPROACH. MATERIALS AND METHODS: AS PART OF THE INTERVENTION, WE DEVELOPED A BOOKLET AND A HIGH-DEFINITION VIDEO FOR PARTICIPANTS AND A MANUAL FOR YOGA-DP INSTRUCTORS. A SYSTEMATIC ITERATIVE PROCESS WAS FOLLOWED TO DEVELOP THE INTERVENTION AND INCLUDED FIVE STEPS: (I) A SYSTEMATIC REVIEW OF THE LITERATURE TO GENERATE A LIST OF YOGIC PRACTICES THAT IMPROVES BLOOD GLUCOSE LEVELS AMONG ADULTS AT HIGH-RISK OF OR WITH T2DM, (II) VALIDATION OF IDENTIFIED YOGIC PRACTICES BY YOGA EXPERTS, (III) DEVELOPMENT OF THE INTERVENTION, (IV) CONSULTATION WITH YOGA, EXERCISE, PHYSICAL ACTIVITY, DIET, BEHAVIOR CHANGE, AND/OR DIABETES EXPERTS ABOUT THE INTERVENTION, AND (V) PRETEST THE INTERVENTION AMONG YOGA PRACTITIONERS AND LAY PEOPLE (THOSE AT RISK OF T2DM AND HAD NOT PRACTICED YOGA BEFORE) IN INDIA. RESULTS: YOGA-DP IS A STRUCTURED LIFESTYLE EDUCATION AND EXERCISE PROGRAM, PROVIDED OVER A PERIOD OF 24 WEEKS. THE EXERCISE PART IS BASED ON YOGA AND INCLUDES SHITHILIKARANA VYAYAMA (LOOSENING EXERCISES), SURYA NAMASKAR (SUN SALUTATION EXERCISES), ASANA (YOGIC POSES), PRANAYAMA (BREATHING PRACTICES), AND DHYANA (MEDITATION) AND RELAXATION PRACTICES. ONCE PARTICIPANTS COMPLETE THE PROGRAM, THEY ARE STRONGLY ENCOURAGED TO MAINTAIN A HEALTHY LIFESTYLE IN THE LONG-TERM. CONCLUSIONS: WE SYSTEMATICALLY DEVELOPED A NOVEL YOGA PROGRAM FOR T2DM PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA. A MULTI-CENTER FEASIBILITY RANDOMIZED CONTROLLED TRIAL IS IN PROGRESS IN INDIA.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       
3  625  33 DIABETIC YOGA PROTOCOL IMPROVES GLYCEMIC, ANTHROPOMETRIC AND LIPID LEVELS IN HIGH RISK INDIVIDUALS FOR DIABETES: A RANDOMIZED CONTROLLED TRIAL FROM NORTHERN INDIA. PURPOSE: TO STUDY THE EFFECTIVENESS OF DIABETIC YOGA PROTOCOL (DYP) AGAINST MANAGEMENT OF CARDIOVASCULAR RISK PROFILE IN A HIGH-RISK COMMUNITY FOR DIABETES, FROM CHANDIGARH, INDIA. METHODS: THE STUDY WAS A RANDOMIZED CONTROLLED TRIAL, CONDUCTED AS A SUB STUDY OF THE PAN INDIA TRIAL NIYANTRITA MADHUMEHA BHARATH (NMB). THE COHORT WAS IDENTIFIED THROUGH THE INDIAN DIABETES RISK SCORING (IDRS) (>/= 60) AND A TOTAL OF 184 INDIVIDUALS WERE RANDOMIZED INTO INTERVENTION (N = 91) AND CONTROL GROUPS (N = 93). THE DYP GROUP UNDERWENT THE SPECIFIC DYP TRAINING WHEREAS THE CONTROL GROUP FOLLOWED THEIR DAILY REGIMEN. THE STUDY OUTCOMES INCLUDED CHANGES IN GLYCEMIC AND LIPID PROFILE. ANALYSIS WAS DONE UNDER INTENT-TO-TREAT PRINCIPLE. RESULTS: THE 3 MONTHS DYP PRACTICE SHOWED DIVERSE RESULTS SHOWING GLYCEMIC AND LIPID PROFILE OF THE HIGH RISK INDIVIDUALS. THREE MONTHS OF DYP INTERVENTION WAS FOUND TO SIGNIFICANTLY REDUCE THE LEVELS OF POST-PRANDIAL GLUCOSE LEVELS (P = 0.035) AND LDL-C LEVELS (P = 0.014) AND WAIST CIRCUMFERENCE (P = 0.001). CONCLUSION: THE FINDINGS INDICATE THAT THE DYP INTERVENTION COULD IMPROVE THE METABOLIC STATUS OF THE HIGH-DIABETES-RISK INDIVIDUALS WITH RESPECT TO THEIR GLUCOSE TOLERANCE AND LIPID LEVELS, PARTIALLY EXPLAINED BY THE REDUCTION IN ABDOMINAL OBESITY. THE STUDY HIGHLIGHTS THE POTENTIAL ROLE OF YOGA INTERVENTION IN REAL TIME IMPROVEMENT OF CARDIOVASCULAR PROFILE IN A HIGH DIABETES RISK COHORT. TRIAL REGISTRATION: CTRI, CTRI/2018/03/012804. REGISTERED 01 MARCH 2018-RETROSPECTIVELY REGISTERED, HTTP://WWW.CTRI.NIC.IN/ CTRI/2018/03/012804.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   
4 1803  31 PREVALENCE OF DIABETES AND ITS DETERMINANTS IN THE YOUNG ADULTS INDIAN POPULATION-CALL FOR YOGA INTERVENTION. BACKGROUND: THE YOUNG INDIAN POPULATION, WHICH CONSTITUTES 65% OF THE COUNTRY, IS FAST ADAPTING TO A NEW LIFESTYLE, WHICH WAS NOT KNOWN EARLIER. THEY ARE AT A HIGH RISK OF THE INCREASING BURDEN OF DIABETES AND ASSOCIATED COMPLICATIONS. THE NEW EVOLVING LIFESTYLE IS NOT ONLY AFFECTING PEOPLE'S HEALTH BUT ALSO MOUNTING THE MONETARY BURDEN ON A DEVELOPING COUNTRY SUCH AS INDIA. AIM: WE AIMED TO COLLECT INFORMATION REGARDING THE PREVALENCE OF RISK OF DIABETES IN YOUNG ADULTS (<35 YEARS) IN THE 29 MOST POPULOUS STATES AND UNION TERRITORIES (7 ZONES) OF INDIA, USING A VALIDATED QUESTIONNAIRE. METHODS: A USER-FRIENDLY QUESTIONNAIRE-BASED SURVEY USING A MOBILE APPLICATION WAS CONDUCTED ON ALL ADULTS IN THE 29 MOST POPULOUS STATES/UNION TERRITORIES OF INDIA, AFTER OBTAINING ETHICAL CLEARANCE FOR THE STUDY. HERE, WE REPORT THE ESTIMATION OF THE PREVALENCE OF THE RISK OF DIABETES AND SELF-REPORTED DIABETES ON 58,821 YOUNG INDIVIDUALS BELOW THE AGE OF 35 YEARS. RISK FOR DIABETES WAS ASSESSED USING A STANDARDIZED INSTRUMENT, THE INDIAN DIABETES RISK SCORE (IDRS), THAT HAS 4 FACTORS (AGE, FAMILY HISTORY OF DIABETES, WAIST CIRCUMFERENCE, AND PHYSICAL ACTIVITY). SPEARMAN'S CORRELATION COEFFICIENT WAS USED TO CHECK THE CORRELATIONS. RESULTS: THE PREVALENCE OF HIGH (IDRS SCORE > 60), MODERATE (IDRS SCORE 30-50), AND LOW (IDRS < 30) DIABETES RISK IN YOUNG ADULTS (<35 YEARS) WAS 10.2%, 33.1%, AND 56.7%, RESPECTIVELY. THOSE WITH HIGH-RISK SCORES WERE HIGHEST (14.4%) IN THE JAMMU ZONE AND LOWEST (4.1%) IN THE CENTRAL ZONE. THE PREVALENCE OF SELF-REPORTED DIABETES WAS 1.8% WITH A SMALL DIFFERENCE BETWEEN MEN (1.7%) AND WOMEN (1.9%), AND THE HIGHEST (8.4%) IN THOSE WITH A PARENTAL HISTORY OF DIABETES. THE SOUTH ZONE HAD THE HIGHEST (2.5%), AND THE NORTH WEST ZONE HAD THE LOWEST (4.4%) PREVALENCE. CONCLUSIONS: INDIAN YOUTH ARE AT HIGH RISK FOR DIABETES, WHICH CALLS FOR AN URGENT ACTION PLAN THROUGH INTENSIVE EFFORTS TO PROMOTE LIFESTYLE BEHAVIOR MODIFICATIONS DURING THE PANDEMICS OF BOTH COMMUNICABLE AND NONCOMMUNICABLE DISEASES.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
5 2763  31 YOGA PROGRAM FOR TYPE 2 DIABETES PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE: QUALITATIVE STUDY TO EXPLORE REASONS FOR NON-PARTICIPATION IN A FEASIBILITY RANDOMIZED CONTROLLED TRIAL IN INDIA. BACKGROUND: YOGA-BASED INTERVENTIONS CAN BE EFFECTIVE IN PREVENTING TYPE 2 DIABETES MELLITUS (T2DM). WE DEVELOPED A YOGA PROGRAM FOR T2DM PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE AND CONDUCTED A FEASIBILITY RANDOMIZED CONTROLLED TRIAL (RCT) IN INDIA. THE OBJECTIVE OF THIS STUDY WAS TO IDENTIFY AND EXPLORE WHY POTENTIAL PARTICIPANTS DECLINED TO PARTICIPATE IN THE FEASIBILITY RCT. METHODS: AN EXPLORATORY QUALITATIVE STUDY, USING SEMI-STRUCTURED INTERVIEWS, WAS CONDUCTED AT A YOGA CENTER IN NEW DELHI, INDIA. FOURTEEN PEOPLE (10 WOMEN AND FOUR MEN) WHO DECLINED TO PARTICIPATE IN THE FEASIBILITY RCT WERE INTERVIEWED, AND 13 OF THEM COMPLETED THE NON-PARTICIPANT QUESTIONNAIRE, WHICH CAPTURED THEIR SOCIO-DEMOGRAPHICS, DIETS, PHYSICAL ACTIVITIES, AND REASONS FOR DECLINING. RESULTS: THREE TYPES OF BARRIERS WERE IDENTIFIED AND EXPLORED WHICH PREVENTED PARTICIPATION IN THE FEASIBILITY RCT: (1) PERSONAL BARRIERS, SUCH AS LACK OF TIME, PERCEIVED SUFFICIENCY OF KNOWLEDGE, PREFERENCES ABOUT SELF-MANAGEMENT OF HEALTH, AND TRUST IN OTHER TRADITIONAL AND ALTERNATIVE THERAPIES; (2) CONTEXTUAL BARRIERS, SUCH AS SOCIAL INFLUENCES AND LACK OF AWARENESS ABOUT PREVENTIVE CARE; AND (3) STUDY-RELATED BARRIERS, SUCH AS LACK OF STUDY INFORMATION, POOR ACCESSIBILITY TO THE YOGA SITE, AND LACK OF TRUST IN THE STUDY METHODS AND INTERVENTION. CONCLUSIONS: WE IDENTIFIED AND EXPLORED PERSONAL, CONTEXTUAL, AND STUDY-RELATED BARRIERS TO PARTICIPATION IN A FEASIBILITY RCT IN INDIA. THE FINDINGS WILL HELP TO ADDRESS RECRUITMENT CHALLENGES IN FUTURE YOGA AND OTHER RCTS. CLINICAL TRIAL REGISTRATION:WWW.CLINICALTRIALS.GOV, IDENTIFIER: CTRI/2019/05/018893.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
6 1251  35 FEASIBILITY TRIAL OF YOGA PROGRAMME FOR TYPE 2 DIABETES PREVENTION (YOGA-DP) AMONG HIGH-RISK PEOPLE IN INDIA: A QUALITATIVE STUDY TO EXPLORE PARTICIPANTS' TRIAL- AND INTERVENTION-RELATED BARRIERS AND FACILITATORS. YOGA-BASED INTERVENTIONS CAN BE EFFECTIVE IN PREVENTING TYPE 2 DIABETES MELLITUS (T2DM). WE DEVELOPED A YOGA PROGRAMME FOR T2DM PREVENTION (YOGA-DP) AND CONDUCTED A FEASIBILITY RANDOMISED CONTROLLED TRIAL (RCT) AMONG HIGH-RISK PEOPLE IN INDIA. THIS QUALITATIVE STUDY'S OBJECTIVE WAS TO IDENTIFY AND EXPLORE PARTICIPANTS' TRIAL- AND INTERVENTION-RELATED BARRIERS AND FACILITATORS. THE FEASIBILITY TRIAL WAS CONDUCTED AT TWO YOGA CENTRES IN NEW DELHI AND BENGALURU, INDIA. IN THIS QUALITATIVE STUDY, 25 TRIAL PARTICIPANTS (13 INTERVENTION GROUP, 12 CONTROL GROUP) WERE RECRUITED FOR SEMI-STRUCTURED INTERVIEWS. DATA WERE ANALYSED USING DEDUCTIVE LOGIC AND AN INTERPRETATIVE PHENOMENOLOGICAL APPROACH. AMONGST INTERVENTION AND CONTROL PARTICIPANTS, KEY BARRIERS TO TRIAL PARTICIPATION WERE INADEQUATE INFORMATION ABOUT RECRUITMENT AND RANDOMISATION PROCESSES AND THE NEGATIVE INFLUENCE OF NON-PARTICIPANTS. FREE BLOOD TESTS TO AID T2DM PREVENTION, SITE STAFF'S FRIENDLY BEHAVIOUR AND FRIENDS' POSITIVE INFLUENCE FACILITATED TRIAL PARTICIPATION. AMONGST INTERVENTION PARTICIPANTS, READABILITY AND UNDERSTANDING OF THE PROGRAMME BOOKLETS, DISLIKE OF THE YOGA DIARY, POOR QUALITY YOGA MATS, DIFFICULTY IN USING THE PROGRAMME VIDEO, HOUSEHOLD COMMITMENT DURING HOME SESSIONS, UNPLANNED TRAVEL, DIFFICULTY IN PRACTISING YOGA POSES, HESITATION IN ATTENDING PROGRAMME SESSIONS WITH THE YOGA-DP INSTRUCTOR OF THE OPPOSITE SEX AND MIXED-SEX GROUP PROGRAMME SESSIONS WERE KEY BARRIERS TO INTERVENTION PARTICIPATION. ADEQUATE INFORMATION WAS PROVIDED ON T2DM PREVENTION AND SELF-CARE, GOOD VENUE AND OTHER SUPPORT PROVIDED FOR PROGRAMME SESSIONS, YOGA-DP INSTRUCTORS' POSITIVE BEHAVIOUR AND IMPROVEMENTS IN PHYSICAL AND MENTAL WELL-BEING FACILITATED INTERVENTION PARTICIPATION. IN CONCLUSION, WE IDENTIFIED AND EXPLORED PARTICIPANTS' TRIAL- AND INTERVENTION-RELATED BARRIERS AND FACILITATORS. WE IDENTIFIED AN ALMOST EQUAL NUMBER OF BARRIERS (N = 12) AND FACILITATORS (N = 13); HOWEVER, INTERVENTION-RELATED BARRIERS AND FACILITATORS WERE GREATER THAN FOR PARTICIPATING IN THE TRIAL. THESE FINDINGS WILL INFORM THE DESIGN OF THE PLANNED DEFINITIVE RCT DESIGN AND INTERVENTION AND CAN ALSO BE USED TO DESIGN OTHER YOGA INTERVENTIONS AND RCTS.	2022	
                                                                                                                                                                                                                                                                                                                                                                                        
7 1092  55 EFFECTS OF YOGA ON UTERO-FETAL-PLACENTAL CIRCULATION IN HIGH-RISK PREGNANCY: A RANDOMIZED CONTROLLED TRIAL. INTRODUCTION. IMPAIRED PLACENTATION AND INADEQUATE TROPHOBLAST INVASION HAVE BEEN ASSOCIATED WITH THE ETIOLOGY OF MANY PREGNANCY COMPLICATIONS AND HAVE BEEN CORRELATED WITH THE FIRST TRIMESTER UTERINE ARTERY RESISTANCE. PREVIOUS STUDIES HAVE SHOWN THE BENEFITS OF YOGA IN IMPROVING PREGNANCY OUTCOMES AND THOSE OF YOGIC VISUALIZATION IN REVITALIZING THE HUMAN TISSUES. METHODS. 59 HIGH-RISK PREGNANT WOMEN WERE RANDOMIZED INTO YOGA (N = 27) AND CONTROL (N = 32) GROUPS. THE YOGA GROUP RECEIVED STANDARD CARE PLUS YOGA SESSIONS (1 HOUR/DAY, 3 TIMES/WEEK), FROM 12TH TO 28TH WEEK OF GESTATION. THE CONTROL GROUP RECEIVED STANDARD CARE PLUS CONVENTIONAL ANTENATAL EXERCISES (WALKING). MEASUREMENTS WERE ASSESSED AT 12TH, 20TH, AND 28TH WEEKS OF GESTATION. RESULTS. RM-ANOVA SHOWED SIGNIFICANTLY HIGHER VALUES IN THE YOGA GROUP (28TH WEEK) FOR BIPARIETAL DIAMETER (P = 0.001), HEAD CIRCUMFERENCE (P = 0.002), FEMUR LENGTH (P = 0.005), AND ESTIMATED FETAL WEIGHT (P = 0.019). THE RESISTANCE INDEX IN THE RIGHT UTERINE ARTERY (P = 0.01), UMBILICAL ARTERY (P = 0.011), AND FETAL MIDDLE CEREBRAL ARTERY (P = 0.048) SHOWED SIGNIFICANTLY LOWER IMPEDANCE IN THE YOGA GROUP. CONCLUSION. THE RESULTS OF THIS FIRST RANDOMIZED STUDY OF YOGA IN HIGH-RISK PREGNANCY SUGGEST THAT GUIDED YOGIC PRACTICES AND VISUALIZATION CAN IMPROVE THE INTRAUTERINE FETAL GROWTH AND THE UTERO-FETAL-PLACENTAL CIRCULATION.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
8 2764  36 YOGA PROGRAMME FOR TYPE-2 DIABETES PREVENTION (YOGA-DP) AMONG HIGH RISK PEOPLE IN INDIA: A MULTICENTRE FEASIBILITY RANDOMISED CONTROLLED TRIAL PROTOCOL. INTRODUCTION: A HUGE POPULATION IN INDIA IS AT HIGH RISK OF TYPE-2 DIABETES (T2DM). PHYSICAL ACTIVITY AND A HEALTHY DIET (HEALTHY LIFESTYLE) IMPROVE BLOOD GLUCOSE LEVELS IN PEOPLE AT HIGH RISK OF T2DM. HOWEVER, AN UNHEALTHY LIFESTYLE IS COMMON AMONG INDIANS. YOGA COVERS PHYSICAL ACTIVITY AND A HEALTHY DIET AND CAN HELP TO PREVENT T2DM. THE RESEARCH QUESTION TO BE ADDRESSED BY THE MAIN RANDOMISED CONTROLLED TRIAL (RCT) IS WHETHER A YOGA PROGRAMME FOR T2DM PREVENTION (YOGA-DP) IS EFFECTIVE IN PREVENTING T2DM AMONG HIGH RISK PEOPLE IN INDIA AS COMPARED WITH ENHANCED STANDARD CARE. IN THIS CURRENT STUDY, WE ARE DETERMINING THE FEASIBILITY OF UNDERTAKING THE MAIN RCT. INTERVENTION: YOGA-DP IS A STRUCTURED LIFESTYLE EDUCATION AND EXERCISE PROGRAMME. THE EXERCISE PART IS BASED ON YOGA AND INCLUDES SHITHILIKARANA VYAYAMA (LOOSENING EXERCISES), SURYA NAMASKAR (SUN SALUTATION EXERCISES), ASANA (YOGIC POSES), PRANAYAMA (BREATHING PRACTICES) AND DHYANA (MEDITATION) AND RELAXATION PRACTICES. METHODS AND ANALYSIS: THIS IS A MULTICENTRE, TWO-ARM, PARALLEL-GROUP, FEASIBILITY RCT WITH BLINDED OUTCOME ASSESSMENT AND INTEGRATED MIXED-METHODS PROCESS EVALUATION. ELIGIBLE PARTICIPANTS SHOULD BE AGED 18-74 YEARS, AT HIGH RISK OF T2DM (FASTING PLASMA GLUCOSE LEVEL 5.6-6.9 MMOL/L) AND SAFE TO PARTICIPATE IN PHYSICAL ACTIVITIES. AT LEAST 64 PARTICIPANTS WILL BE RANDOMISED TO INTERVENTION OR CONTROL GROUP WITH FINAL FOLLOW-UP AT 6 MONTHS. IMPORTANT PARAMETERS, NEEDED TO DESIGN THE MAIN RCT, WILL BE ESTIMATED, SUCH AS SD OF THE OUTCOME MEASURE (FASTING PLASMA GLUCOSE LEVEL AT 6-MONTH FOLLOW-UP), RECRUITMENT, INTERVENTION ADHERENCE, FOLLOW-UP, POTENTIAL CONTAMINATION AND TIME NEEDED TO CONDUCT THE STUDY. SEMISTRUCTURED QUALITATIVE INTERVIEWS WILL BE CONDUCTED WITH UP TO 20-30 PARTICIPANTS, A SAMPLE OF THOSE DECLINING TO PARTICIPATE, FOUR YOGA-DP INSTRUCTORS AND AROUND EIGHT STUDY STAFF TO EXPLORE THEIR PERCEPTIONS AND EXPERIENCES OF TAKING PART IN THE STUDY AND OF THE INTERVENTION, REASONS BEHIND NON-PARTICIPATION, EXPERIENCES OF DELIVERING THE INTERVENTION AND RUNNING THE STUDY, RESPECTIVELY. ETHICS AND DISSEMINATION: ETHICS APPROVAL HAS BEEN OBTAINED FROM THE FOLLOWING RESEARCH ETHICS COMMITTEES: FACULTY OF MEDICINE AND HEALTH SCIENCES, UNIVERSITY OF NOTTINGHAM (UK); CENTRE FOR CHRONIC DISEASE CONTROL (CCDC, INDIA); BAPU NATURE CURE HOSPITAL AND YOGASHRAM (BNCHY, INDIA) AND SWAMI VIVEKANANDA YOGA ANUSANDHANA SAMSTHANA (S-VYASA, INDIA). THE RESULTS WILL BE WIDELY DISSEMINATED AMONG KEY STAKEHOLDERS THROUGH VARIOUS AVENUES. TRIAL REGISTRATION NUMBER: CTRI/2019/05/018893.	2020	
                                                                           
9  926  32 EFFECTIVENESS OF YOGA LIFESTYLE ON LIPID METABOLISM IN A VULNERABLE POPULATION-A COMMUNITY BASED MULTICENTER RANDOMIZED CONTROLLED TRIAL. BACKGROUND: DYSLIPIDEMIA POSES A HIGH RISK FOR CARDIOVASCULAR DISEASE AND STROKE IN TYPE 2 DIABETES (T2DM). THERE ARE NO STUDIES ON THE IMPACT OF A VALIDATED INTEGRATED YOGA LIFESTYLE PROTOCOL ON LIPID PROFILES IN A HIGH-RISK DIABETES POPULATION. METHODS: HERE, WE REPORT THE RESULTS OF LIPID PROFILE VALUES OF 11,254 (YOGA 5932 AND CONTROL 5322) ADULTS (20-70 YEARS) OF BOTH GENDERS WITH HIGH RISK (>/=60 ON INDIAN DIABETES RISK SCORE) FOR DIABETES FROM A NATIONWIDE RURAL AND URBAN COMMUNITY-BASED TWO GROUP (YOGA AND CONVENTIONAL MANAGEMENT) CLUSTER RANDOMIZED CONTROLLED TRIAL. THE YOGA GROUP PRACTICED A VALIDATED INTEGRATED YOGA LIFESTYLE PROTOCOL (DYP) IN NINE DAY CAMPS FOLLOWED BY DAILY ONE-HOUR PRACTICE. BIOCHEMICAL PROFILING INCLUDED GLYCATED HEMOGLOBIN AND LIPID PROFILES BEFORE AND AFTER THREE MONTHS. RESULTS: THERE WAS A SIGNIFICANT DIFFERENCE BETWEEN GROUPS (P < 0.001 ANCOVA) WITH IMPROVED SERUM TOTAL CHOLESTEROL, TRIGLYCERIDES, LOW-DENSITY LIPOPROTEIN, AND HIGH-DENSITY LIPOPROTEIN IN THE YOGA GROUP COMPARED TO THE CONTROL GROUP. FURTHER, THE REGULATORY EFFECT OF YOGA WAS NOTED WITH A SIGNIFICANT DECREASE OR INCREASE IN THOSE WITH HIGH OR LOW VALUES OF LIPIDS, RESPECTIVELY, WITH MARGINAL OR NO CHANGE IN THOSE WITHIN THE NORMAL RANGE. CONCLUSION: YOGA LIFESTYLE IMPROVES AND REGULATES (LOWERED IF HIGH, INCREASED IF LOW) THE BLOOD LIPID LEVELS IN BOTH GENDERS OF PREDIABETIC AND DIABETIC INDIVIDUALS IN BOTH RURAL AND URBAN INDIAN COMMUNITIES.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
10 2145  30 THE EFFECTS OF MINDFULNESS EATING AND YOGA EXERCISE ON BLOOD SUGAR LEVELS OF PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS. AIM: THIS RANDOMIZED CONTROLLED TRIAL WAS CARRIED OUT TO INVESTIGATE THE EFFECT OF MINDFULNESS EATING AND YOGA EXERCISE ON BLOOD SUGAR LEVELS AMONG PREGNANT THAI WOMEN WITH GDM. BACKGROUND: INTERVENTIONS PROMOTING ACHIEVEMENT OF GOOD GLYCEMIC CONTROL RESULT IN DESIRED PREGNANCY OUTCOMES. LITTLE IS KNOWN ABOUT THE HEALTH BENEFITS OF MINDFULNESS EATING AND YOGA EXERCISE ON BLOOD SUGAR LEVELS AMONG PREGNANT WITH GDM. METHODS: A RANDOMIZED CONTROLLED TRIAL WAS CARRIED OUT. MAIN OUTCOME MEASURES WERE CAPILLARY FASTING PLASMA GLUCOSE, 2-H POSTPRANDIAL BLOOD GLUCOSE, AND HEMOGLOBIN A1C. RESULTS: THE INTERVENTION GROUP SHOWED SIGNIFICANTLY REDUCED FASTING PLASMA GLUCOSE, 2-H POSTPRANDIAL BLOOD GLUCOSE, AND GLYCOSYLATED HEMOGLOBIN (HBA1C) IN THE INTERVENTION GROUP (P<0.05). CONCLUSIONS: MINDFULNESS EATING AND YOGA EXERCISE HAD HEALTH BENEFITS ON GLYCEMIC CONTROL IN PREGNANT WOMEN WITH GDM. IT SHOULD BE RECOMMENDED IN CLINICAL AND COMMUNITY HEALTH SERVICES.	2014	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
11 2584  52 YOGA FOR HIGH-RISK PREGNANCY: A RANDOMIZED CONTROLLED TRIAL. BACKGROUND: IMPROVEMENTS IN TECHNOLOGY HAVE INCREASED THE CHANCES OF SURVIVAL FOR THE MICRO-PREMATURE INFANT AND THE VERY LOW BIRTH-WEIGHT INFANT BUT HAVE SIGNIFICANTLY INCREASED THE FINANCIAL BURDEN OF HEALTH CARE ORGANIZATIONS. THIS ECONOMIC BURDEN HAS A SIGNIFICANT IMPACT ON THIRD-PARTY PAYERS AND ON SOCIETY IN GENERAL. AIM: THE STUDY WAS DESIGNED TO ASSESS YOGA THERAPY (YT) MODULE ON MATERNAL STRESS LEVEL IN HIGH RISK PREGNANCY. SUBJECTS AND METHODS: IN THE PRESENT STUDY, SIXTY-EIGHT PREGNANT WOMEN (38 IN THE CONTROL GROUP WITH STANDARD ANTENATAL CARE AND 30 IN THE YT GROUP) WITH 27.2 (5.2) YEARS OF MEAN AGE RECRUITED FROM THE OUTPATIENT SERVICES OF MEDICAL COLLEGE AND HOSPITAL IN BANGALORE, SOUTH INDIA, WERE PARTICIPATED. THE STUDY WAS A SINGLE-BLIND RANDOMIZED CONTROLLED CLINICAL TRIAL. PERCEIVED STRESS SCALE (PSS) WAS MEASURED DURING THE 12(TH), 20(TH), AND 28(TH) WEEKS OF PREGNANCY. SPSS VERSION 16.0 (CHICAGO, IL, USA) WAS USED FOR ALL DATA ANALYSIS. WHEN THE DATA WERE FOUND TO BE NORMALLY DISTRIBUTED, THE RMANOVA WERE USED TO ASSESS THE PSS SCORES BETWEEN THE YOGA AND CONTROL GROUPS. SIGNIFICANT VALUES WERE SET AT P < 0.05. RESULTS: THERE WAS A SIGNIFICANT DIFFERENCE IN THE PSS LEVEL OF THE YT GROUP WITH SIGNIFICANTLY REDUCED SCORES AT THE SECOND FOLLOW-UP (28(TH) WEEK OF PREGNANCY) COMPARED TO THE CONTROL GROUP (P = 0.02). WOMEN WHO TOOK PART IN THE YT MODULE REPORTED SIGNIFICANTLY FEWER PREGNANCY DISCOMFORTS DECREASE IN PSS (P = 0.02) THAN THE CONTROL GROUP WHERE THE STRESS LEVEL WAS INCREASED (RMANOVA TEST USING SPSS-16). CONCLUSION: THE PRESENT STUDY SUGGESTS THAT THE YT MODULE CAN DECREASE THE STRESS LEVEL DURING HIGH-RISK PREGNANCY COMPLICATIONS. THUS, PRACTICING YT DURING HIGH-RISK PREGNANCY IS NOT ONLY A COST-EFFECTIVE OPTION BUT ALSO A FEASIBLE AND SAFE OPTION. ADDITIONAL WELL-DESIGNED STUDIES ARE NEEDED BEFORE A STRONG RECOMMENDATION CAN BE MADE.	2013	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
12 1040  40 EFFECTS OF YOGA INTERVENTION DURING PREGNANCY: A REVIEW FOR CURRENT STATUS. OBJECTIVES: THE PURPOSE OF THIS ARTICLE IS TO REVIEW ALL RANDOMIZED CONTROL TRIALS (RCTS) THAT HAVE LOOKED AT THE HEALTH EFFECTS OF YOGA ON PREGNANCY, AND TO PRESENT THEIR EVIDENCE ON THE SPECIFIC WAYS IN WHICH PREGNANT WOMEN, AND THEIR INFANTS CAN BENEFIT FROM YOGA INTERVENTION. THE PURPOSE IS ALSO TO DETERMINE WHETHER YOGA INTERVENTION DURING PREGNANCY IS MORE BENEFICIAL THAN OTHER PHYSICAL EXERCISES. METHODS: FOUR DATABASES WERE SEARCHED USING THE TERMS "YOGA AND (PREGNANCY OR PREGNANT OR PRENATAL OR POSTNATAL OR POSTPARTUM)." DATABASES WERE SEARCHED FROM JANUARY 2004 TO FEBRUARY 2014. RESULTS: TEN RANDOMIZED CONTROLLED TRIALS WERE EVALUATED. THE FINDINGS CONSISTENTLY INDICATE THAT YOGA INTERVENTION PRESENTED WITH LOWER INCIDENCES OF PRENATAL DISORDERS (P </= 0.05), AND SMALL GESTATIONAL AGE (P < 0.05), LOWER LEVELS OF PAIN AND STRESS (P < 0.05), AND HIGHER SCORE OF RELATIONSHIP (P < 0.05). IN ADDITION, YOGA CAN BE SAFELY USED FOR PREGNANT WOMEN WHO ARE DEPRESSED, AT HIGH-RISK, OR EXPERIENCE LUMBOPELVIC PAIN. MOREOVER, YOGA IS A MORE EFFECTIVE EXERCISE THAN WALKING OR STANDARD PRENATAL EXERCISES. CONCLUSIONS: THE FINDINGS SUGGEST THAT YOGA IS A SAFE AND MORE EFFECTIVE INTERVENTION DURING PREGNANCY. HOWEVER, FURTHER RCTS ARE NEEDED TO PROVIDE FIRMER EVIDENCE REGARDING THE UTILITY AND VALIDITY OF YOGA INTERVENTION.	2015	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
13 1538  31 KNOWLEDGE AND ATTITUDES TOWARD PRENATAL YOGA AMONG WOMEN WITH HIGH-RISK PREGNANCIES. THIS STUDY SOUGHT TO EVALUATE ATTITUDES AND KNOWLEDGE ABOUT PRENATAL YOGA AND TO INVESTIGATE BARRIERS AND FACILITATORS TO YOGA PARTICIPATION IN HIGH-RISK PREGNANT WOMEN RECEIVING PRENATAL CARE IN AN ACADEMIC TERTIARY CARE CENTER. WE SURVEYED A CONVENIENCE SAMPLE OF WOMEN RECEIVING PRENATAL CARE THROUGH THE MATERNAL-FETAL MEDICINE PRACTICE AT BRIGHAM AND WOMEN'S HOSPITAL. WE CLASSIFIED PARTICIPANTS AS YOGA-EXPERIENCED OR YOGA-NAIVE DEPENDING ON SELF-REPORT. WE COMPARED DIFFERENCES BETWEEN THE TWO GROUPS USING THE APPROPRIATE NONPARAMETRIC TESTS AND COMPARED BIVARIATE ODDS RATIOS FOR SURVEY RESULTS USING LOGISTIC REGRESSION. OF THE 100 RESPONDENTS, 53% HAD PRACTICED YOGA PREVIOUSLY. WOMEN WITH YOGA EXPERIENCE WERE OLDER (AGE 34.9 +/- 5.6 VS. 31.0 +/- 6.0 YEARS, P = 0.004), MORE LIKELY TO BE COLLEGE GRADUATES (94% VS. 68%, P = 0.002), AND MORE LIKELY TO BE WHITE (77% VS. 47%, P = 0.002) THAN WOMEN WITHOUT PREVIOUS YOGA EXPERIENCE. PREVIOUS YOGA EXPERIENCE WAS ASSOCIATED WITH PARTICIPANT AGREEMENT THAT YOGA WAS SAFE DURING THEIR CURRENT PREGNANCY (ODDS RATIO 5.9, 95% CONFIDENCE INTERVAL 1.9-17.7). OF THE WOMEN SURVEYED, 56% AGREED THAT THEY WOULD LIKE TO ATTEND A PRENATAL YOGA CLASS. IN A MULTIVARIATE MODEL INCLUDING AGE, RACE, AND EDUCATION, PREVIOUS YOGA EXPERIENCE WAS THE ONLY SIGNIFICANT PREDICTOR ASSOCIATED WITH WILLINGNESS TO PARTICIPATE IN PRENATAL YOGA CLASSES DURING CURRENT PREGNANCY (ODDS RATIO 3.1, 95% CONFIDENCE INTERVAL 1.1-8.6). PRIOR YOGA EXPERIENCE WAS THE STRONGEST PREDICTOR OF WILLINGNESS TO ATTEND A PRENATAL YOGA CLASS IN OUR POPULATION. OUR RESULTS SUGGEST THAT WOMEN WITH HIGH-RISK PREGNANCIES WHO MAY BENEFIT FROM PRENATAL YOGA INTERVENTIONS BUT LACK PRIOR YOGA EXPERIENCE MAY NEED ADDITIONAL EDUCATION TO FACILITATE PARTICIPATION.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
14  140  29 A PROSPECTIVE STUDY ON TYPE-2 DIABETIC COMPLICATIONS AND EFFICACY OF INTEGRATED YOGA: A PAN INDIA 2017. BACKGROUND: TYPE 2 DIABETES (T2DM) CONTRIBUTES TO HIGH MORTALITY AND MORBIDITY BECAUSE OF ITS MAJOR COMPLICATIONS RELATED TO KIDNEY, HEART, BRAIN, AND EYES. IT ALSO POSES A HIGH RISK FOR MORTALITY BECAUSE OF COVID-19. STUDIES SUGGEST THE POSSIBLE IMPLICATIONS OF YOGA IN DELAYING OR ATTENUATING SUCH COMPLICATIONS. METHODOLOGY: THIS WAS A PAN-INDIA MULTI CENTERED CLUSTER-RANDOMIZED (4 LEVEL) TWO-ARMED TRIAL IN THE RURAL AND URBAN POPULATION OF ALL POPULOUS STATES OF INDIA. DATA WERE OBTAINED USING MOBILE APP IN ALL ADULTS IN THE HOUSEHOLD OF THE SELECTED CLUSTERS. RESULTS: WE REPORT THE DIABETES RELATED COMPLICATIONS IN 16623 ADULTS (48% MALES, 52% FEMALES) FROM 65 DISTRICTS (1 IN 10 DISTRICTS, 2011 CENSUS) OF 29 (OUT OF 35) STATES AND UNION TERRITORIES OF INDIA; MEAN AGE WAS 48.2 +/- 12.46 YEARS. OUT OF THIS 40% LIVED IN RURAL AND 62% IN URBAN LOCATIONS. IN HIGH RISK DIABETES INDIVIDUALS (SCORED >/= 60 POINTS ON INDIAN DIABETES RISK SCORE KEY), 18.0% HAD SELF-REPORTED HISTORY OF (PERIPHERAL NEUROPATHY, 6.1% HAD H/O MAJOR STROKES, 5.5% HAD MINOR STROKES (TRANSIENT ISCHEMIC EPISODES), 18.1% HAD LOWER LIMB CLAUDICATION, 20.5% LEG ULCERS, 4.4% HAD H/O CARDIAC SURGERY, 4.8% ANGIOPLASTY, AND 15.1% HAD DIABETES RETINOPATHY. COMPLICATIONS WERE HIGHER IN RURAL THAN IN URBAN AREAS, HIGHER IN PEOPLE WITH EXTENDED DURATION OF DIABETES. INTEGRATED YOGA MODULE FOR THREE MONTHS (ONE HOUR DAILY) SHOWED SIGNIFICANTLY BETTER REDUCTION IN SYMPTOMS RELATED TO COMPLICATIONS AS COMPARED TO CONTROL GROUP (P < .001). CONCLUSION: THE ALARMING HIGH PREVALENCE OF COMPLICATIONS IN DIABETES POPULATION CALLS FOR URGENT ACTION, WHERE YOGA MAY SHOW THE BENEFITS IN REDUCTION OF SYMPTOMS OF COMPLICATIONS.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     
15  688  43 EFFECT OF ANTENATAL EXERCISES, INCLUDING YOGA, ON THE COURSE OF LABOR, DELIVERY AND PREGNANCY: A RETROSPECTIVE STUDY. BACKGROUND: DELIVERING A CHILD IS A VERY STRESSFUL EXPERIENCE FOR WOMEN. PREGNANCY AND LABOR ENTAIL COMPLEX EVENTS THAT ARE UNIQUE TO EACH INDIVIDUAL FEMALE. THE MANAGEMENT OF LABOR PAIN IS OFTEN DONE USING ANALGESICS AND ANESTHESIA, WHICH HAVE BEEN SHOWN TO HAVE SOME SIDE EFFECTS. MORE COMPREHENSIVE DATA ARE NEEDED TO PROVIDE CLINICALLY SIGNIFICANT EVIDENCE FOR CLINICIANS TO CONFIDENTLY PRESCRIBE EXERCISES TO PATIENTS. THIS STUDY WAS DONE TO EVALUATE THE EFFECT OF ANTENATAL EXERCISES, INCLUDING YOGA, ON THE COURSE OF LABOR, DELIVERY, AND PREGNANCY OUTCOMES. METHODS: A RETROSPECTIVE STUDY WAS CONDUCTED AMONG 200 PRIMIPAROUS SUBJECTS (AGED 20-40). A QUESTIONNAIRE WAS PROVIDED TO THE SUBJECTS TO OBTAIN THEIR DEMOGRAPHIC AND OBSTETRICAL INFORMATION 6 WEEKS AFTER DELIVERY, AND THEIR HOSPITAL RECORDS WERE ALSO ASSESSED FOR FURTHER DETAILS. BASED ON THE NATURE AND DETAILS OBTAINED FOR THE ANTENATAL EXERCISES, SUBJECTS WERE DIVIDED INTO TWO GROUPS: CONTROL AND EXERCISE. OUTCOME MEASURES INCLUDED THE NEED FOR LABOR INDUCTION, SELF-PERCEIVED PAIN AND PERCEIVED EXERTION DURING LABOR, DURATION AND NATURE OF THE DELIVERY, NEWBORN INFANT WEIGHT, MATERNAL WEIGHT GAIN, HISTORY OF BACK PAIN, AND POST-PARTUM RECOVERY. THE TOTAL MATERNAL WEIGHT GAIN (IN KILOGRAMS) WAS CALCULATED FROM WEIGHT AT 6 WEEKS AFTER DELIVERY MINUS THE WEIGHT AT 12-14 WEEKS OF GESTATION. BACK PAIN DURING PREGNANCY AND SELF-PERCEIVED LABOR PAIN WERE MEASURED USING A VISUAL ANALOG SCALE (VAS). THE OVERALL PERCEIVED EXERTION DURING LABOR WAS MEASURED USING AN ADAPTED BORG SCALE FOR PERCEIVED EFFORT. RESULTS: THE SUBJECTS WHO FOLLOWED REGULAR ANTENATAL EXERCISES, INCLUDING YOGA, HAD SIGNIFICANTLY LOWER RATES OF CESAREAN SECTION, LOWER WEIGHT GAIN, HIGHER NEWBORN INFANT WEIGHT, LOWER PAIN AND OVERALL DISCOMFORT DURING LABOR, LOWER BACK PAIN THROUGHOUT PREGNANCY, AND EARLIER POST-PARTUM RECOVERY COMPARED TO THOSE WHO DID NO SPECIFIC EXERCISES OR ONLY WALKED DURING PREGNANCY. CONCLUSIONS: THIS RETROSPECTIVE STUDY SHOWED THAT REGULAR ANTENATAL EXERCISES, INCLUDING YOGA, RESULT IN BETTER OUTCOMES RELATED TO THE COURSE OF LABOR, DELIVERY, AND PREGNANCY. THESE RESULTS NOTABLY INDICATED THAT PREGNANT WOMEN SHOULD BE ACTIVE THROUGHOUT PREGNANCY AND FOLLOW A SUPERVISED EXERCISE PROGRAM THAT INCLUDES YOGA UNLESS CONTRAINDICATED. WE REQUIRE FURTHER LARGE-SCALE PROSPECTIVE STUDIES AND QUASI-EXPERIMENTAL TRIALS TO CONFIRM THE OBSERVED FINDINGS.	2020	
                                                                                                                                                                                                                                                                                 
16 2523  31 YOGA DURING PREGNANCY: A REVIEW. THE PURPOSE OF THIS REVIEW ARTICLE IS TO EVALUATE THE PERIPARTUM OUTCOMES OF YOGA DURING PREGNANCY, INCLUDING THE POSTPARTUM PERIOD AND LACTATION. THE PUBMED DATABASE WAS ANALYZED FROM JANUARY 1970 TO JANUARY 2011. WE IDENTIFIED FIVE PROSPECTIVE OBSERVATIONAL STUDIES (N = 575) AND THREE RANDOMIZED CLINICAL TRIALS (RCTS; N = 298), WHICH WERE ANALYZED SEPARATELY. THE NONRANDOMIZED TRIALS INDICATED A SIGNIFICANT REDUCTION IN RATES OF PRETERM LABOR (P < 0.0006), INTRAUTERINE GROWTH RETARDATION (P <0.003), LOW BIRTH WEIGHT (P < 0.01), PREGNANCY DISCOMFORTS (P = 0.01), AND PERCEIVED SLEEP DISTURBANCES (P = 0.03) IN THOSE WHO PRACTICED YOGA DURING PREGNANCY. RESULTS OF THE RCTS INDICATED THAT DOING YOGA DURING PREGNANCY CAN SIGNIFICANTLY LOWER PAIN AND DISCOMFORT (P < 0.05) AND PERCEIVED STRESS (P = 0.001) AND IMPROVE QUALITY OF LIFE IN PHYSICAL DOMAINS (P = 0.001). ALL THREE RCTS WERE POORLY COMPLIANT WITH THE CONSOLIDATED STANDARD OF REPORTING TRIALS STATEMENT. WHILE AWAITING AN APPROPRIATELY DESIGNED RCT TO DETERMINE THE BENEFITS OF YOGA DURING PREGNANCY, IT REMAINS A VIABLE EXERCISE OPTION.	2012	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
17  183  35 A RANDOMIZED CONTROLLED TRIAL ON THE EFFICACY OF INTEGRATED YOGA ON PREGNANCY OUTCOME. PHYSIOLOGICAL AND BIOCHEMICAL CHANGES OCCUR IN PREGNANCY TO NURTURE THE DEVELOPING FETUS. PREGNANCY-RELATED EXPERIENCE IS UNIQUE TO EVERY WOMAN. PREGNANCY SYMPTOMS AND COMPLICATIONS CAN RANGE FROM MILD TO SEVERE. MANY WOMEN CAN LOWER THEIR RISK BY PERFORMING DIFFERENT THERAPIES. IN THIS CONTEXT, THE PRESENT STUDY TARGETS TO EVALUATE THE EFFICACY OF INTEGRATED YOGA CONSISTING OF (ASANAS AND PRANAYAMA) ON PREGNANCY TO REDUCE THE RISK OF COMPLICATIONS. THIS STUDY IS A PROSPECTIVE RANDOMIZED CONTROLLED SINGLE-BLINDED TRIAL WITH PARALLEL ARMS: THE INTERVENTION ARM RECEIVED SPECIFIC INTEGRATED YOGA THERAPY; THE CONTROL ARM RECEIVED ROUTINE STANDARD CARE FROM 18 TO 22 WEEKS OF GESTATION UNTIL DELIVERY. THE INCIDENCE OF PREECLAMPSIA AND PRETERM DELIVERY WAS LOWER IN THE INTERVENTION ARM. WOMEN IN THE INTERVENTION ARM DELIVERED AT HIGHER GESTATIONAL AGE. APGAR SCORES AND BIRTH WEIGHTS OF NEONATES WERE SIGNIFICANTLY HIGHER IN THE INTERVENTION ARM. THE FINDINGS SUGGEST THAT YOGA IS A SAFE AND EFFECTIVE INTERVENTION DURING PREGNANCY TO REDUCE OR PREVENT PREGNANCY-RELATED COMPLICATIONS. HOWEVER, FURTHER RANDOMIZED CONTROLLED TRIALS ARE NEEDED TO PROVIDE FIRMER EVIDENCE REGARDING THE UTILITY AND VALIDITY OF YOGA INTERVENTION DURING PREGNANCY.	2021	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
18 1136  46 EFFICACY OF YOGA ON PREGNANCY OUTCOME. OBJECTIVE: TO STUDY THE EFFICACY OF YOGA ON PREGNANCY OUTCOMES. DESIGN AND SETTING: THREE HUNDRED THIRTY FIVE (335) WOMEN ATTENDING THE ANTENATAL CLINIC AT GUNASHEELA SURGICAL AND MATERNITY HOSPITAL IN BANGALORE, INDIA, WERE ENROLLED BETWEEN 18 AND 20 WEEKS OF PREGNANCY IN A PROSPECTIVE, MATCHED, OBSERVATIONAL STUDY; 169 WOMEN IN THE YOGA GROUP AND 166 WOMEN IN THE CONTROL GROUP. METHODS: WOMEN WERE MATCHED FOR AGE, PARITY, BODY WEIGHT, AND DOPPLER VELOCIMETRY SCORES OF UMBILICAL AND UTERINE ARTERIES. YOGA PRACTICES, INCLUDING PHYSICAL POSTURES, BREATHING, AND MEDITATION WERE PRACTICED BY THE YOGA GROUP ONE HOUR DAILY, FROM THE DATE OF ENTRY INTO THE STUDY UNTIL DELIVERY. THE CONTROL GROUP WALKED 30 MINUTES TWICE A DAY (STANDARD OBSTETRIC ADVICE) DURING THE STUDY PERIOD. COMPLIANCE IN BOTH GROUPS WAS ENSURED BY FREQUENT TELEPHONE CALLS AND STRICT MAINTENANCE OF AN ACTIVITY DIARY. MAIN OUTCOMES: BIRTH WEIGHT AND GESTATIONAL AGE AT DELIVERY WERE PRIMARY OUTCOMES. RESULTS: THE NUMBER OF BABIES WITH BIRTH WEIGHT > OR = 2500 GRAMS WAS SIGNIFICANTLY HIGHER (P < 0.01) IN THE YOGA GROUP. PRETERM LABOR WAS SIGNIFICANTLY LOWER (P < 0.0006) IN THE YOGA GROUP. COMPLICATIONS SUCH AS ISOLATED INTRAUTERINE GROWTH RETARDATION (IUGR) (P < 0.003) AND PREGNANCY-INDUCED HYPERTENSION (PIH) WITH ASSOCIATED IUGR (P < 0.025) WERE ALSO SIGNIFICANTLY LOWER IN THE YOGA GROUP. THERE WERE NO SIGNIFICANT ADVERSE EFFECTS NOTED IN THE YOGA GROUP. CONCLUSIONS: AN INTEGRATED APPROACH TO YOGA DURING PREGNANCY IS SAFE. IT IMPROVES BIRTH WEIGHT, DECREASES PRETERM LABOR, AND DECREASES IUGR EITHER IN ISOLATION OR ASSOCIATED WITH PIH, WITH NO INCREASED COMPLICATIONS.	2005	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  
19 1471  34 INPATIENT PRENATAL YOGA SESSIONS FOR WOMEN WITH HIGH-RISK PREGNANCIES: A FEASIBILITY STUDY. BACKGROUND: ANTENATAL HOSPITALIZATION FOR PREGNANCY COMPLICATIONS CAN RESULT IN SIGNIFICANT STRESS FOR PREGNANT WOMEN AND THEIR FAMILIES. PRENATAL YOGA HAS BEEN INVESTIGATED IN THE OUTPATIENT SETTING AS A METHOD TO ALLEVIATE STRESS. THIS STUDY WAS DESIGNED TO INVESTIGATE THE FEASIBILITY OF INCORPORATING PRENATAL YOGA INTO THE INPATIENT ENVIRONMENT FOR WOMEN HOSPITALIZED WITH PREGNANCY COMPLICATIONS. STUDY DESIGN: HIGH-RISK WOMEN WERE RECRUITED FROM THE INPATIENT ANTEPARTUM SERVICE AT TUFTS MEDICAL CENTER (BOSTON, MA; MARCH 2016 TO FEBRUARY 2017) TO EVALUATE THE FEASIBILITY OF AN INPATIENT PRENATAL YOGA PROGRAM. THE THIRTY-MINUTE SESSION WAS LED BY A CERTIFIED INSTRUCTOR IN A ROOM ADJACENT TO LABOR AND DELIVERY. PARTICIPANTS AND ANTEPARTUM NURSES COMPLETED STUDY QUESTIONNAIRES ADDRESSING LOGISTICS SUCH AS CLASS DURATION AND FREQUENCY. PERCEIVED BENEFITS OF YOGA WERE ALSO EXPLORED. RESULTS: THIRTY-NINE WOMEN WERE FOUND ELIGIBLE FOR THIS STUDY AND WERE CONSENTED FOR PARTICIPATION. OF THESE, FIFTEEN (38%) PARTICIPATED IN AT LEAST ONE YOGA SESSION. RESPONSES TO THE TO THE POST-CLASS QUESTIONNAIRE BY STUDY PARTICIPANTS INDICATED THAT THE THIRTY MINUTES ALLOCATED FOR THE YOGA CLASS WAS APPROPRIATE. OF THE EIGHT PARTICIPANTS WHO RESPONDED TO THE DISCHARGE QUESTIONNAIRE, ALL INDICATED THAT THE CLASS WAS HELPFUL WITH REGARDS TO STRESS REDUCTION. COMPLETED QUESTIONNAIRES BY THE ANTEPARTUM NURSING STAFF (N = 14) UNANIMOUSLY INDICATED THAT THE YOGA SESSION WAS HELPFUL FOR THE PATIENTS AND WAS NOT DISRUPTIVE TO MEDICAL CARE. CONCLUSION(S): PRENATAL YOGA IS A TECHNIQUE THAT HAS BEEN CURRENTLY LIMITED TO THE OUTPATIENT SETTING. THIS STUDY PROVIDES A FOUNDATION FOR CONTINUED INVESTIGATION OF INPATIENT PRENATAL YOGA FOR WOMEN HOSPITALIZED WITH PREGNANCY COMPLICATIONS.	2020	
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
20 2899  53 [EFFECTS OF PRENATAL YOGA: A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS]. OBJECTIVES: WHILE SEVERAL STUDIES ON THE PREVENTIVE AND THERAPEUTIC EFFECTS OF PRENATAL YOGA (MATERNITY YOGA) HAVE BEEN REPORTED IN RECENT YEARS, THERE HAS BEEN NO SYSTEMATIC REVIEW ON THE EFFECTS OF PRENATAL YOGA BASED ON RANDOMIZED CONTROLLED TRIALS (RCT). THE PURPOSE OF THIS STUDY, THEREFORE, WAS TO SYSTEMATICALLY REVIEW THE LITERATURE TO CLARIFY THE EFFECTS OF PRENATAL YOGA IN RCT FOCUSING ON THE CONTENTS OF THE INTERVENTION, THE INTERVENTION MEANS, AND THE FREQUENCY OF PRACTICE. METHODS: THE LITERATURE SEARCH WAS PERFORMED USING THE ELECTRONIC DATABASE, PUBMED. THE INCLUSION CRITERIA WERE RCT, PREGNANT WOMEN, AND YOGA INTERVENTION. RESULTS: IN TOTAL, 54 CITATIONS WERE FOUND; OF THESE, EIGHT STUDIES (10 REPORTS) WERE INCLUDED IN THE FINAL ANALYSIS. IN FOUR STUDIES ON HEALTHY PREGNANT WOMEN, SIGNIFICANT IMPROVEMENT IN PAIN AND PLEASURE AT DELIVERY, DURATION OF DELIVERY, PERCEIVED STRESS LEVELS DURING PREGNANCY, ANXIETY LEVELS, DEPRESSION, PREGNANCY-RELATED EXPERIENCES, QUALITY OF LIFE, AND INTERPERSONAL RELATIONSHIPS WERE COMPARED TO THOSE IN THE CONTROL GROUP. IN TWO STUDIES ON DEPRESSED PREGNANT WOMEN, ONE REPORTED THAT DEPRESSION, ANXIETY LEVELS, ANGER LEVELS, LEG PAIN, AND BACK PAIN SIGNIFICANTLY IMPROVED WITH YOGA, WHILE THE OTHER FOUND NO DIFFERENCES FROM THE CONTROL GROUP. IN ONE STUDY OF HIGH-RISK PREGNANT WOMEN WITH MORBIDITY FACTORS SUCH AS OBESITY OR ADVANCED AGE, YOGA RESULTED IN SIGNIFICANTLY FEWER CASES OF PREGNANCY-INDUCED HYPERTENSION, GESTATIONAL DIABETES, AND INTRAUTERINE GROWTH RESTRICTION, AS WELL AS A DECREASE IN PERCEIVED STRESS LEVELS. IN ONE STUDY ON PREGNANT WOMEN WITH PELVIC PAIN, THE MEDIAN PAIN SCORE WAS LOWER IN THE YOGA GROUP. REGARDING THE CONTENTS OF THE INTERVENTION, WHILE THE TWO STUDIES FOR DEPRESSED PREGNANT WOMEN ONLY INCLUDED PHYSICAL POSTURES, THE REMAINING SIX STUDIES ALSO INCLUDED BREATHING TECHNIQUE AND MEDITATION. INTERVENTIONS WERE PERFORMED USING LECTURES BY INSTRUCTORS ALONE OR TOGETHER WITH SELF-TEACHING. THE FREQUENCY OF THE INTERVENTION VARIED WITHIN EACH STUDY. CONCLUSION: THE FINDINGS SUGGEST THAT PRENATAL YOGA MAY HELP REDUCE PELVIC PAIN. IT MAY ALSO IMPROVE MENTAL CONDITION (STRESS, DEPRESSION, ANXIETY, ETC.), PHYSICAL CONDITION (PAIN AND PLEASURE AT THE DELIVERY, ETC.), AND PERINATAL OUTCOMES (OBSTETRICAL COMPLICATIONS, DELIVERY TIME, ETC.). HOWEVER, FURTHER STUDIES ARE NEEDED. THE CONTENTS OF THE INTERVENTION, THE INTERVENTION MEANS, AND THE FREQUENCY VARIED WITH EACH STUDY. THUS, IT IS NECESSARY TO FURTHER EXAMINE THE CONTENT OF EFFECTIVE INTERVENTIONS, INTERVENTION MEANS, AND FREQUENCY THAT SUIT PARTICIPANT'S CHARACTERISTICS AND EACH OUTCOME. FURTHER RESEARCH IN THIS FIELD, PARTICULARLY RANDOMIZED CONTROLLED TRIALS, IS MERITED.	2015